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Evidence that spinal cord thyrotropin-releasing hormone is independent oft he paraventricular nucleus

Identifieur interne : 000B35 ( Main/Exploration ); précédent : 000B34; suivant : 000B36

Evidence that spinal cord thyrotropin-releasing hormone is independent oft he paraventricular nucleus

Auteurs : Ronald M. Lechan [États-Unis] ; Scott B. Snapper [États-Unis] ; Ivor M. D. Jackson [États-Unis]

Source :

RBID : ISTEX:923E027A56CEE3BCAC98D25E29C4B5EA52F327F5

Abstract

To determine whether neuronal perikarya containing thyrotropin-releasing hormone (TRH) in the paraventricular nucleus project to the spinal cord, this region of the hypothalamus was ablated by a midline electrolytic lesion and the spinal cord assayed for its content of TRH. In contrast to the marked diminution of TRH in the median eminence, there was no significant change in the TRH content in the spinal cord. These results indicate the absence of significant afferent input of TRH-containing perikarya in the paraventricular nucleus to the spinal cord.

Url:
DOI: 10.1016/0304-3940(83)90129-5


Affiliations:


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Le document en format XML

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<div type="abstract" xml:lang="en">To determine whether neuronal perikarya containing thyrotropin-releasing hormone (TRH) in the paraventricular nucleus project to the spinal cord, this region of the hypothalamus was ablated by a midline electrolytic lesion and the spinal cord assayed for its content of TRH. In contrast to the marked diminution of TRH in the median eminence, there was no significant change in the TRH content in the spinal cord. These results indicate the absence of significant afferent input of TRH-containing perikarya in the paraventricular nucleus to the spinal cord.</div>
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